HS
HS
  • Home
  • Our team
  • OUR SERVICES
  • Blog
  • OUR RESEARCH
  • NEWS
  • Contact Us
  • More
    • Home
    • Our team
    • OUR SERVICES
    • Blog
    • OUR RESEARCH
    • NEWS
    • Contact Us
  • Home
  • Our team
  • OUR SERVICES
  • Blog
  • OUR RESEARCH
  • NEWS
  • Contact Us

OUR RESEARCH

 The research team, Washington Institute of Clinical Research, has consistently dedicated itself to clinical research, emphasizing areas such as autoimmune diseases, neurologic diseases, cancer, and rare diseases. We use advanced methods of big data analysis to drive forward our research endeavors and contribute to medical advancements. 

PUBLICATIONS

MemTrax memory test for Alzheimer’s Disease

 

  1. Liu W, Yu L, Deng Q, Li Y, Lu P, Yang J, Chen F, Li F, Zhou X, Bergeron MF, Ashford JW, Xu Q. Toward digitally screening and profiling AD: A GAMLSS approach of MemTrax in China. Alzheimers Dement. 2023 Aug 31. doi: 10.1002/alz.13430. Epub ahead of print. PMID: 37654085.
  2. Zhao X, Dai S, Zhang R, Chen X, Zhao M, Bergeron MF, Zhou X, Zhang J, Zhong L, Ashford JW, Liu X. Using MemTrax memory test to screen for post-stroke cognitive impairment after ischemic stroke: a cross-sectional study. Front Hum Neurosci. 2023 Jul 17;17:1195220. doi: 10.3389/fnhum.2023.1195220. PMID: 37529406; PMCID: PMC10387538.
  3. Chen W, Lin C, Su F, Fang Y, Liu G, Chen YC, Zhou X, Yao X, Ashford CB, Li F, Ashford JW, Fu QL, Pei Z. Early Diagnosis of Mild Cognitive Impairment due to Alzheimer's Disease Using a Composite of MemTrax and Blood Biomarkers. J Alzheimers Dis. 2023;94(3):1093-1103. doi: 10.3233/JAD-230182. PMID: 37355900.
  4. Ashford JW, Schmitt FA, Bergeron MF, Bayley PJ, Clifford JO, Xu Q, Liu X, Zhou X, Kumar V, Buschke H, Dean M, Finkel SI, Hyer L, Perry G. Now is the Time to Improve Cognitive Screening and Assessment for Clinical and Research Advancement. J Alzheimers Dis. 2022;87(1):305-315. doi: 10.3233/JAD-220211. PMID: 35431257.
  5. Liu X, Chen X, Zhou X, Shang Y, Xu F, Zhang J, He J, Zhao F, Du B, Wang X, Zhang Q, Zhang W, Bergeron MF, Ding T, Ashford JW, Zhong L. Validity of the MemTrax Memory Test Compared to the Montreal Cognitive Assessment in the Detection of Mild Cognitive Impairment and Dementia due to Alzheimer's Disease in a Chinese Cohort. J Alzheimers Dis. 2021;80(3):1257-1267. doi: 10.3233/JAD-200936. PMID: 33646151.
  6. Bergeron MF, Landset S, Zhou X, Ding T, Khoshgoftaar TM, Zhao F, Du B, Chen X, Wang X, Zhong L, Liu X, Ashford JW. Utility of MemTrax and Machine Learning Modeling in Classification of Mild Cognitive Impairment. J Alzheimers Dis. 2020;77(4):1545-1558. doi: 10.3233/JAD-191340. PMID: 32894241; PMCID: PMC7683062.
  7. Zhou X, Ashford JW. Advances in screening instruments for Alzheimer's disease. Aging Med (Milton). 2019 May 31;2(2):88-93. doi: 10.1002/agm2.12069. PMID: 31942517; PMCID: PMC6880670.

Autoimmune Disease

 

  1. Li HY, Xia M, Song M, Xie Y, Wang Q, Yue YX, Li HF. Rs1800629 polymorphism in TNF-alpha is associated with the susceptibility and initial short-term glucocorticoids efficacy in myasthenia gravis patients. J Neuroimmunol. 2024 Feb 15;387:578269. doi: 10.1016/j.jneuroim.2023.578269. 
  2. Li HY, Jiang P, Xie Y, Liang B, Li L, Zhao C, Yue YX, Li HF. Criteria for Treatment Response in Myasthenia Gravis: Comparison Between Absolute Change and Improvement Percentage in Severity Scores. Front Neurol. 2022 Jun 2;13:880040. doi: 10.3389/fneur.2022.880040. PMID: 35720071; PMCID: PMC9201395.
  3. Han JL, Yue YX, Gao X, Xie YC, Hao HJ, Li HY, Yu XL, Li J, Duan RS, Li HF. Vitamin D Receptor Polymorphism and Myasthenia Gravis in Chinese Han Population. Front Neurol. 2021 Feb 9;12:604052. doi: 10.3389/fneur.2021.604052. PMID: 33633666; PMCID: PMC7900549.
  4. Yue YX, Gao X, Tang TP, Xie Y, Gu CK, Hao HJ, Li HY, Ding XJ, Song M, Guo SG, Li HF. Complement C3 polymorphism is associated with the susceptibility of myasthenia gravis in Chinese adult patients. J Neuroimmunol. 2021 Apr 15;353:577487. doi: 10.1016/j.jneuroim.2021.577487. Epub 2021 Jan 30. PMID: 33578311.
  5. Cai GM, Gao Z, Yue YX, Xie YC, Gao X, Hao HJ, Zhang XJ, Wang Q, Liang B, Li HF. Association between CTLA-4 gene polymorphism and myasthenia gravis in a Chinese cohort. J Clin Neurosci. 2019 Nov;69:31-37. doi: 10.1016/j.jocn.2019.08.079. Epub 2019 Aug 28. PMID: 31473094.
  6. Jiang P, Yue YX, Hong Y, Xie Y, Gao X, Gu CK, Hao HJ, Qin Y, Ding XJ, Song M, Li HF, Zhang X. IL-4Rα Polymorphism Is Associated With Myasthenia Gravis in Chinese Han Population. Front Neurol. 2018 Jul 10;9:529. doi: 10.3389/fneur.2018.00529. PMID: 30042722; PMCID: PMC6048264.

Medical Bibliometrics and Big Data Analysis

  1. Wen Q, Cao L, Yang C, Xie Y. The Electrophysiological Features in X-Linked Charcot-Marie-Tooth Disease With Transient Central Nervous System Deficits. Front Neurol. 2018 Jun 27;9:461. doi: 10.3389/fneur.2018.00461. PMID: 30013503; PMCID: PMC6036262. 

cANCER rESEARCH

  1. Cao Y, He M, Liu Z, Chen K, Denis K 1st, Zhang J, Zou J, Semchenko BS, Efetov SK. Evaluation of the efficacy of natural orifice specimen extraction surgery versus conventional laparoscopic surgery for colorectal cancers: A systematic review and meta-analysis. Colorectal Dis. 2025 Jan;27(1):e17279. doi: 10.1111/codi.17279. PMID: 39763245.
  2. Bai J, Wang Z, Yang M, Xiang J, Liu Z. Disrupting CENP-N mediated SEPT9 methylation as a strategy to inhibit aerobic glycolysis and liver metastasis in colorectal cancer. Clin Exp Metastasis. 2024 Dec;41(6):971-988. doi: 10.1007/s10585-024-10316-z. 
  3.  Yang YX, Tang Y, Li N, Tang Y, Cheng YJ, Yang L, Fang H, Lu NN, Qi SN, Chen B, Wang SL, Song YW, Liu YP, Li YX, Liu Z, Liang JW, Zhang HZ, Zhou HT, Wang J, Liu WY, Jin J. Comprehensive geriatric assessment guided radiotherapy in elderly patients with locally advanced rectal cancer-exploratory results on nonoperative cohort of a multicenter prospective study. Ther Adv Med Oncol. 2024 Nov 19;16:17588359241296386. doi: 10.1177/17588359241296386. PMID: 39563720; PMCID: PMC11574900.
  4.  Cao Y, He M, Chen K, Liu Z, Khlusov DI, Khorobrykh TV, Cao X, Panova PD, Efetov SK, Kazaryan AM. Short- and long-term outcomes after surgical treatment of 5918 patients with splenic flexure colon cancer by extended right colectomy, segmental colectomy and left colectomy: a systematic review and meta-analysis. Front Oncol. 2024 Apr 15;14:1244693. doi: 10.3389/fonc.2024.1244693. PMID: 38686198; PMCID: PMC11057231.

Copyright © 2016 Healsan - All Rights Reserved.

Powered by

This website uses cookies.

We use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.

Accept